Why does the spontaneous deamination of cytosine not affect the distribution of dinucleotide pairs in prokaryote genomes? - Cuntorio

Bacteria usually do not methylate cytosine residues and do not use methyl CpG as a means of regulating gene expression. Bacteria typically methylate adenine residues, which protect genomic DNA from restriction by restriction endonucleases and tag the parent strand during mismatch repair.