How does the spontaneous deamination of cytosine affect the distribution of dinucleotide pairs in eukaryote genomes?
Deamination of cytosine yields uracil, which is thought to be why DNA has evolved to contain methyl uracil (thymine), to enable the correction of this chemically inevitable corruption of the coded message. However, there are regions of the genome that contain significantly higher proportions of methyl cytosine, often preceding a G in the sequence. These regions are associated with gene silencing
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