Some characteristics of Oncogenes and tumour suppressor genes - Cuntorio

Dominant gain-of-function mutations in proto-oncogenes and recessive loss-of-function mutations in tumor-suppressor genes are oncogenic. Among the proteins encoded by proto-oncogenes are positive-acting growth factors and their receptors, signal-transduction proteins, transcription factors, and cell-cycle control proteins. An activating mutation of one of the two alleles of a proto-oncogene