Why do hemoglobin subunits associate to form a tetramer while myoglobin does not? - Cuntorio

Although the amino acid sequences of myoglobin and hemoglobin are homologous, and they adopt the same globin fold, there are important differences in patches where the polypeptide chains in hemoglobin make contact with one another. In particular, some of the surface residues that are polar in myoglobin are hydrophobic in hemoglobin; e.g.,residue B15 (the 15th residue in helix B) is a lysine in